CBD and Melatonin: The Next Sleep Aid?

CBD and Melatonin_ The Next Sleep Aid (2)

If you’re struggling with sleep, you’ve probably heard of CBD and melatonin as separate treatments. But what if you want to take them together to see if they work well as a sleep aid?

So, is it safe to take CBD with melatonin?

CBD oil and melatonin are both natural substances that help the body keep up with its regular functions. CBD and melatonin work differently in the body, but they both may help with sleep.

Melatonin is a hormone that helps to regulate the body’s sleep-wake cycle, while CBD oil can help to ease anxiety and pain. Both melatonin and CBD oil may help people fall asleep and stay asleep. They are both safe and effective for most people.

In this article, we take a closer look at whether you can take CBD and melatonin together, the benefits that they provide for the body, and anything you need to be aware of before you start.


Can I Take CBD With Melatonin?

CBD and melatonin are both natural substances that have been shown to support the body’s overall health. Some people wonder if it is safe to take CBD with melatonin and what the effects might be.

CBD and melatonin are both known to help with sleep, but they can also have opposite effects. CBD has been shown to disrupt sleep, while melatonin can offset this effect.

This has the potential to work together, and it is why CBD and melatonin can be so complementary as you work to maintain a better sleep cycle. Research has also proved favourable in the combination of CBD and melatonin.

Taking CBD and melatonin together may help you to get a good night’s sleep without the CBD disrupting your slumber.

However, it is important to remember that taking other natural products with melatonin can be disruptive in a negative way as well. This is why you should always consult with your doctor first to ensure that your choice to mix CBD and melatonin is going to work for you.

Can I Take CBD With Melatonin?

What is Melatonin?

Melatonin is a hormone that helps to regulate the body’s sleep-wake cycle, and it is naturally produced in the pineal gland. The pineal gland is located in the brain, and it is responsible for secreting melatonin.

Melatonin production is highest at night, and it helps to signal to the body that it is time to sleep. This hormone can also be taken as a supplement to help with sleep.

Melatonin supplements are often used to help with jet lag or shift work sleep disorder, and they can also be helpful for people who have difficulty falling asleep or staying asleep.


What is CBD Oil?

CBD oil is a natural substance that is derived from the cannabis plant. CBD oil does not contain THC, the psychoactive component of marijuana, so it does not produce a high.

CBD oil has a number of potential health benefits, including the ability to ease anxiety and pain. CBD oil may also help to improve sleep.

CBD oil works by interacting with the body’s endocannabinoid system. The endocannabinoid system helps to regulate a number of important functions, including sleep, appetite, pain, and immune system function.

CBD oil may help to improve sleep by interacting with receptors in the body. CBD oil may also help to reduce anxiety and pain, which can both interfere with sleep.


What are the Benefits of Melatonin?

If you are considering taking melatonin to help with your sleep, there are several potential benefits that it can provide – especially to those with delayed sleep phase syndrome.

Makes it Easier to Fall Asleep

Melatonin supplements can help to ease you into sleep by making it easier for you to fall asleep.

Regulates Sleep Cycle

Studies have shown that melatonin also helps to keep your sleep cycle regulated. This means that you will be less likely to experience waking up in the middle of the night and having difficulty falling back asleep.

Helps You Stay Asleep

In addition to making it easier for you to fall asleep, melatonin can also help you stay asleep for a longer period of time.

It does this by continuing to work in the background to regulate your sleep cycle, which can help you stay asleep for a more restful night.


What are the Benefits of CBD for Sleep?

If you decide to take CBD, CBD oil, or CBD gummies for sleep, there are also several benefits to doing this.

Just remember that it is often better to take CBD during the day to aid with sleep as it can disrupt your sleep cycle when taken too close to bedtime.

Reduces Anxiety

CBD is known to help reduce anxiety, which can be a major cause of insomnia. CBD oil can help to ease your anxiety so that you can fall asleep more easily, and the research supports this.

CBD can Help with Pain Relief

If you experience pain that is keeping you awake at night, studies have shown that CBD oil may be able to help. CBD is known to help with pain relief, and this can make it easier for you to fall asleep and stay asleep.

Reduces Stress

CBD oil may also help to reduce stress, which can be another major cause of insomnia. CBD can help to ease your stress so that you can fall asleep and stay asleep more easily, leading to better quality sleep.

Helps Maintain Healthy Sleep Cycles

CBD may also help to maintain healthy sleep cycles, according to a recent review. This means that it can help you fall asleep more easily and stay asleep for a more restful night.


What are the Side Effects of Melatonin?

Before you take melatonin, it is important to be aware of the potential side effects. While melatonin is generally safe for most people, there are a few potential side effects that you should be aware of, as stated by the Mayo Clinic.

The most common side effect of melatonin is drowsiness. This means that you may feel tired during the day if you take melatonin at night.

Other potential side effects of melatonin include:

  • Nausea
  • Headaches
  • Dizziness
  • Grogginess


What are the Side Effects of CBD?

CBD is generally considered to be safe, and there have been studies to show that it is practically impossible to overdose on it.

However, there is the potential to experience some negative side effects when you take it. According to research, these side effects include:

  • Drowsiness
  • Dizziness and lightheadedness
  • Dry Mouth
  • Diarrhea
  • Increased Appetite 
  • Lowered blood pressure
  • Drug interactions with prescription medications

What are the Side Effects of Mixing CBD and Melatonin?

What are the Side Effects of Mixing CBD and Melatonin?

The side effects of taking CBD with melatonin will depend on the dosage of each that you take.

While they can both work as sleep medications, this doesn’t mean that they will always react well together.

If you take too much melatonin, you may experience drowsiness, headaches, dizziness, or nausea. If you take too much CBD, you may experience drowsiness, dry mouth, diarrhea, or increased appetite.

However, there is also the potential to experience these side effects when they are taken together:

  • Lethargy
  • Drowsiness
  • Vivid dreaming

The good news is that these are not severe side effects, but if you feel concerned, you should stop taking them right away and talk to your doctor.


Can You Overdose on Melatonin?

It is possible to overdose on melatonin, but it is very difficult to do so. The average person would have to take about 10,000 times the recommended dosage of melatonin in order to overdose on it.

However, even taking a large amount of melatonin is not likely to be fatal, and there have been studies on the toxicology of melatonin. The most common side effect of an overdose is drowsiness.

If you do overdose on melatonin, it is important to seek medical attention right away and get checked out just to be safe.

This is also true if you start to feel unwell after taking it as it is possible to have severe (and fatal) allergic reactions to melatonin.


To Conclude

You can take CBD products, like UNO CBD sleep gummies, with melatonin, and doing so may provide you with some potential benefits. These benefits include making it easier to fall asleep and stay asleep, reducing anxiety and stress, and maintaining healthy sleep cycles.

However, there is the potential to experience some side effects when taking CBD with melatonin. Be sure to consult with your doctor beforehand to ensure that it is safe for you to take CBD with melatonin.

We hope that you find the perfect balance to help you sleep and that you find a combination of CBD and melatonin to be helpful to you during this.

Learn more about CBD and cannabis-related topics at Weed Delivery Vancouver.



Iffland K, Grotenhermen F. An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis Cannabinoid Res. 2017 Jun 1;2(1):139-154. doi: 10.1089/can.2016.0034. PMID: 28861514; PMCID: PMC5569602. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569602/

Huestis MA, Solimini R, Pichini S, Pacifici R, Carlier J, Busardò FP. Cannabidiol Adverse Effects and Toxicity. Curr Neuropharmacol. 2019;17(10):974-989. doi: 10.2174/1570159X17666190603171901. PMID: 31161980; PMCID: PMC7052834. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7052834/

Guardiola-Lemaître B. Toxicology of melatonin. J Biol Rhythms. 1997 Dec;12(6):697-706. doi: 10.1177/074873049701200627. PMID: 9406047.

 Available at: https://pubmed.ncbi.nlm.nih.gov/9406047/

Norml. (2022, February 17). Study: Insomnia Patients Respond Favorably to Concurrent Use of CBD and Melatonin. Available at: https://norml.org/news/2022/02/17/study-insomnia-patients-respond-favorably-to-concurrent-use-of-cbd-and-melatonin/

Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi: 10.7812/TPP/18-041. PMID: 30624194; PMCID: PMC6326553. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/

Argueta DA, Ventura CM, Kiven S, Sagi V, Gupta K. A Balanced Approach for Cannabidiol Use in Chronic Pain. Front Pharmacol. 2020 Apr 30;11:561. doi: 10.3389/fphar.2020.00561. PMID: 32425793; PMCID: PMC7204604. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204604/

Babson KA, Sottile J, Morabito D. Cannabis, Cannabinoids, and Sleep: a Review of the Literature. Curr Psychiatry Rep. 2017 Apr;19(4):23. doi: 10.1007/s11920-017-0775-9. PMID: 28349316. Available at: https://pubmed.ncbi.nlm.nih.gov/28349316/

Bauer, Brent. (2022). Is melatonin a helpful sleep aid — and what should I know about melatonin side effects? Available at: https://www.mayoclinic.org/healthy-lifestyle/adult-health/expert-answers/melatonin-side-effects/faq-20057874

Costello RB, Lentino CV, Boyd CC, O’Connell ML, Crawford CC, Sprengel ML, Deuster PA. The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Nutr J. 2014 Nov 7;13:106. doi: 10.1186/1475-2891-13-106. PMID: 25380732; PMCID: PMC4273450. Available at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4273450/

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